|
KMID : 0360220180590080724
|
|
Journal of the Korean Ophthalmological Society
2018 Volume.59 No. 8 p.724 ~ p.729
|
|
|
Anti-pseudomonal Effect of a Nephrite-containing Contact Lens Storage Case
|
|
Lee Sang-Min
Jung Jae-Woo
Lee Dong-Hyun
Park Sung-Hee
Lee Jong-Heon
Yu Hak-Sun
Kim Yoon-Kyung
Lee Ji-Eun
|
|
|
Abstract
|
|
|
Purpose: To compare the anti-pseudomonal effect of nephrite-containing contact lens (CL) storage cases with conventional CL storage cases.
Methods: The degree of proliferation and adhesion of Pseudomonas aeruginosa (P. aeruginosa) on 1st?3rd generation silicone hydrogel contact lenses (SHCLs) was compared by using both 5% nephrite-containing CL storage cases and conventional CL storage cases. The degree of adhesion of P. aeruginosa to the CL was also compared in 1% or 5% nephrite solution and multipurpose solution (MPS).
Results: Nephrite-containing CL storage cases showed a significant inhibitory effect on P. aeruginosa proliferation (p = 0.03) and significantly reduced the number of adherent P. aeruginosa on all 1st?3rd generation SHCLs compared with conventional CL storage cases (p = 0.02, p = 0.03, and p < 0.01, respectively). There was no significant anti-pseudomonal effect of 1% and 5% nephrite solutions compared with MPS.
Conclusions: Nephrite may be the next generation substance that reduces infectious keratitis caused by P. aeruginosa when added to CL storage cases.
|
|
|
KEYWORD
|
|
|
Contact lens storage case, Infectious keratitis, Multipurpose solution, Nephrite, Pseudomonas aeruginosa
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|